The Manufacturing sector saw plenty of trading activity today, including the following leaders and losers.

Some of the biggest gainers among Manufacturing stocks include:

Valeant Pharmaceuticals International (VRX): VRX stock is up 11.93% today.

Advaxis Inc Cmn Stk (ADXS): ADXS stock is up 12.74% today.

Celator Pharma Cmn (CPXX): CPXX stock is up 9.77% today.

Tantech Holdings Cmn (TANH): TANH stock is up 10.76% today.

Aduro Biotech Cmn (ADRO): ADRO stock is up 10.44% today.

Prothena Corp (PRTA): PRTA stock is up 9.54% today.

Ovascience Cmn Stk (OVAS): OVAS stock is up 15.68% today.

Horizon Pharma Ord (HZNP): HZNP stock is up 8.42% today.

Intra-Cellular Ther (ITCI): ITCI stock is up 9.19% today.

Cara Therapeutics (CARA): CARA stock is up 11.8% today.

Some of the biggest losers among Manufacturing stocks include:

Nortech Systems In (NSYS): NSYS stock is down 10.54% today.

Affymetrix Inc (AFFX): AFFX stock is down 10.44% today.

Kura Oncology Cmn (KURA): KURA stock is down 8.99% today.

Biostar Pharmaceutic (BSPM): BSPM stock is down 3.95% today.

Workhorse Grp Cmn ST (WKHS): WKHS stock is down 8.1% today.

Trinseo S.A. (TSE): TSE stock is down 6.21% today.

Wave Life Sci Ord Sh (WVE): WVE stock is down 5.07% today.

United States Steel Corp (X): X stock is down 6.54% today.

Sunedison Inc (SUNE): SUNE stock is down 6.1% today.

Leading Brands (LBIX): LBIX stock is down 5.96% today.

For more information on the best stocks to buy right now, check out the latest commentary on InvestorPlace.com.

And for more on the hot stocks moving most on Wall Street right now, check out our archive of daily market movers by sector here.

Editor’s Note: Returns for the fastest-moving stocks listed here are based on share prices 20 minutes prior to publication of this story.