Healthcare stocks advanced broadly on Wall Street on Wednesday morning, with the sector seeing an overall increase of 0.6%.

More broadly, the Dow Jones Industrial Average remained flat, the Nasdaq increased 0.3% and the S&P 500 was unchanged.

Some of the biggest gainers among healthcare stocks include:

• Puma Biotechnology (PBYI): PBYI stock is up 281.3% today and up 221.5% in the last month.

• Inovio Pharmaceuticals (INO): INO stock is up 25.1%, marking the third consecutive day the stock has increased.

• Intuitive Surgical (ISRG): ISRG stock is up 12.6%, marking the fifth consecutive day the stock has increased.

• Biogen Idec Inc (BIIB): BIIB stock is up 11.9% today.

• Neogen Corp (NEOG): NEOG stock is up 8.2% today.

• Celldex Therapeutics Inc (CLDX): CLDX stock is up 4.6% today.

• Isis Pharmaceuticals (ISIS): ISIS stock is up 3.3% today.

• Acorda Therapeutics (ACOR): ACOR stock is up 3.1% today.

• Ironwood Pharmaceuticals (IRWD): IRWD stock is up 3.0% today.

• Biomarin Pharmaceutical Inc (BMRN): BMRN stock is up 2.8%, marking the fourth consecutive day the stock has increased.

Some of the biggest losers among healthcare stocks include:

• Cubist Pharmaceuticals (CBST): CBST stock is down 5.9% today.

• Glaxosmithkline Plc (GSK): GSK stock is down 4.5%, marking the third consecutive day the stock has decreased.

• Theravance (THRX): THRX stock is down 3.0%, marking the third consecutive day the stock has decreased.

• Tenet Healthcare Corp (THC): THC stock is down 1.5% today.

• Community Health Systems (CYH): CYH stock is down 1.3% today.

• Kindred Healthcare (KND): KND stock is down 1.1% today.

• Express Scripts (ESRX): ESRX stock is down 1.2% today.

• The Medicines Company (MDCO): MDCO stock is down 1.0% today.

• Brookdale Senior Living Inc (BKD): BKD stock is down 1.0% today.

• Emeritus Corp (ESC): ESC stock is down 1.0% today.

For more information on the best stocks to buy right now, check out the latest commentary on InvestorPlace.com.

And for more on the hot stocks moving most on Wall Street right now, check out our archive of daily market movers by sector here.

Editor’s Note: Returns for the fastest-moving stocks listed here are based on share prices 20 minutes prior to publication of this story.