In early trading Wednesday, names such as Northwest Biotherapeutics (NWBO) and Organovo Holdings (ONVO) would among the stocks that were the biggest stock losers.

Here are the other stock losers that started out having a very bad day, with a trading volume of over 1 million.

Take a look at today’s biggest stock losers.

Biggest Stock Losers

Northwest Biotherapeutics (NWBO, -23.5%): Northwest Biotherapeutics was one of Monday’s biggest stock losers, after announcing a common stock offering. NWBO stock lost severely after months of gains, which were spurred by its development of immunotherapy products to fights cancers.

Organovo Holdings (ONVO, -11.4%): For a second day in a row, ONVO stock was a huge loser, with yesterday’s fall only making matters worse for the stock.

Seaspan Corp (SSW, -9.6%): Seaspan Corporation lost nearly 10% in early trading after pricing previously announced common shares at $22 . SSW stock is still up 32% year to date.

Intercloud (ICLD, -10%): After jumping to a nearly one-year high, Intercloud — a huge winner just days ago — stumbled a bit, falling some 10% as the stock struggled to regain its footing.

Voxeljet AG (VJET, -9.2%): Voxeljet AG just yesterday saw its VJET stock offerings jump 19%, but has fallen today more than 9%. Year to date it’s still up some 56%.

J.M. Smucker Company (SJM, -5.7%): SJM stock took a fall after Q2 earnings, which showed a 2% drop in sales. While SJM is up some 18% year to date, the poor Q2 report doesn’t look like it bodes well for the company in the near future.