This week, the overall grades of five pharmaceutical stocks are lower, according to the Portfolio Grader database. Each of these rates a “D” (“sell”) or “F” overall (“strong sell”).

This week, Bio-Path Holdings, Inc. (BPTH) falls to a D (“sell”), worse than last week’s grade of C (“hold”). In Portfolio Grader’s specific subcategory of Equity, BPTH also gets an F. For more information, get Portfolio Grader’s complete analysis of BPTH stock.

This week, Alcobra Ltd. (ADHD) drops from a C to a D rating. The stock gets F’s in Earnings Momentum, Equity and Cash Flow. To get an in-depth look at ADHD, get Portfolio Grader’s complete analysis of ADHD stock.

This is a rough week for Prestige Brands Holdings, Inc. (PBH). The company’s rating falls to D from the previous week’s C. Prestige Brands distributes over-the-counter healthcare and household cleaning products to retail stores in the United States, Canada and other international markets. The stock also rates an F in Earnings Growth. The stock’s trailing PE Ratio is 35.70. For more information, get Portfolio Grader’s complete analysis of PBH stock.

Lipocine, Inc. (LPCN) ratings are on the decline this week as the company earns an F (“strong sell”). Last week, it received a D (“sell”). Lipocine is engaged in the development of pharmaceutical products in the areas of men’’s and women’’s health. The stock gets F’s in Earnings Revisions, Equity and Cash Flow. To get an in-depth look at LPCN, get Portfolio Grader’s complete analysis of LPCN stock.

AcelRx Pharmaceuticals, Inc. (ACRX) gets weaker ratings this week as last week’s C drops to a D. AcelRx Pharmaceuticals focuses on the development and commercialization of therapies for the treatment of acute and breakthrough pain. The stock also gets an F in Earnings Momentum. As of Jan. 9, 2015, 20.7% of outstanding AcelRx Pharmaceuticals, Inc. shares were held short. For more information, get Portfolio Grader’s complete analysis of ACRX stock.

Louis Navellier’s proprietary Portfolio Grader stock ranking system assesses roughly 5,000 companies every week based on a number of fundamental and quantitative measures. Stocks are given a letter grade based on their results — with A being “strong buy,” and F being “strong sell.” Explore the tool here.