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The 3 Best Biotech ETF Investments

Get direct exposure to the biotech sector with these funds

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SPDR S&P Biotech ETF (XBI)

Total Assets Under Management: $1 billion
Expense Ratio: 0.35%

biotech etf xbiAnother option in the biotech ETF universe is the cheaper SPDR S&P Biotech ETF (XBI), which boasts an expense ratio of just 0.35%.

For better or for worse, the SPDR S&P Biotech ETF is a smaller fund than the IBB. It has $1 billion in net assets, less than half the number of holdings and a much smaller average market cap for those biotech stocks.

The holdings in this completely pure biotech ETF boast an average market cap around $3 billion and are pretty evenly distributed. No holding makes up more than 3%.

The top three biotech stocks in this fund are Opko Health (OPK), Halozyme Therapeutics (HALO) and Sarepta Therapeutics (SRPT).

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